PCR genetic analysis has been in the spotlight since COVID-19, but light is now further facilitating PCR-free methods. Osaka Metropolitan University scientists have developed a light-induced DNA detection technique, using heterogeneous probe particles, that enables ultra-sensitive and ultra-fast genetic analysis without the need for PCR amplification. This advancement is paving the way for faster, more affordable, and precise genetic analysis across medicine, environmental science, and portable diagnostics.
Shining a light on DNA: A rapid, ultra-sensitive, PCR-free detection method
