Study demonstrates that mpox vaccine antibody responses wane within a year

A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has demonstrated that mpox antibody levels declined rapidly and nearly returned to baseline six to 12 months after patients received the mpox vaccination. The findings, published in JAMA, suggest that protective immunity may have waned in previously vaccinated individuals and that boosting may be required to maintain robust protection.

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