New nasal vaccine has potential to transform respiratory disease prevention

A research team from Trinity College Dublin has unveiled a new approach to vaccination that could redefine how we protect against respiratory infections. In a study published in Nature Microbiology, the team demonstrate that their nasally delivered, antibiotic-inactivated Bordetella pertussis (AIBP) vaccine not only prevents severe disease but also curbs bacterial transmission—an achievement long sought by vaccine developers worldwide.

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