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MedicalXpress.com – Vaccines

MedicalXpress.com – Vaccines

‘Low-sugar’ vaccine can provide broad immunity against coronavirus variants

March 25, 2025

Sugar coatings aren’t only for candies; they also help viruses, like the ones that cause COVID-19, hide from their hosts’ immune system. Now, researchers have developed a universal vaccine that targets coronaviruses and the sugars […]

MedicalXpress.com – Vaccines

Protecting immunocompromised children from measles as the disease continues to spread

March 20, 2025

Adult antibody thresholds are currently used to determine whether immunocompromised children should get a measles, mumps, and rubella (MMR) booster shot. However, a new study shows that these thresholds fail to identify a significant percentage […]

MedicalXpress.com – Vaccines

Single vaccine dose shows 84% effectiveness against mpox, but insufficient for HIV patients

March 19, 2025

Universitätsmedizin Berlin has found that a single dose of the Imvanex vaccine provides protection against mpox with 84% effectiveness. For people with HIV, however, a single dose of the vaccine fails to offer sufficient protection. […]

MedicalXpress.com – Vaccines

Built-in safeguard in B cell populations could impact vaccine design

March 19, 2025

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells adapted to keep different pathogens in check. But rapid […]

MedicalXpress.com – Vaccines

New understanding of B cell mutation strategies could have implications for vaccines

March 19, 2025

A vaccine’s ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating in hopes of generating the most […]

MedicalXpress.com – Vaccines

H5N1 influenza viral lineages beginning to evade human immunological defenses, research finds

March 19, 2025

New computational modeling of avian influenza variants’ immunoprotein interactions—developed by a research team at the University of North Carolina at Charlotte—reveals the H5N1 influenza virus is evolving to escape immunological defenses raised by previous infection […]

MedicalXpress.com – Vaccines

The relationship between gut microbiota, immunoglobulin A, and vaccine efficacy

March 13, 2025

Gut microbiota may be the key factor explaining why certain individuals do not respond well to the pneumococcal vaccine, a bacterium that can cause various diseases, such as pneumonia. This conclusion is drawn from a […]

MedicalXpress.com – Vaccines

Study highlights gaps in HPV-related cancer prevention for people living with HIV

March 12, 2025

A new study published in The Lancet HIV reveals gaps in knowledge surrounding the prevention of HPV-related cancers in people living with HIV and outlines future research priorities.This post was originally published on this site

MedicalXpress.com – Vaccines

Meningococcal vaccine found to be safe and effective for infants in sub-Saharan Africa

March 12, 2025

University of Maryland School of Medicine (UMSOM) researchers helped conduct an important new global health study that found a vaccine that protects against five strains of meningitis prevalent in sub-Saharan Africa is safe and effective […]

MedicalXpress.com – Vaccines

A more affordable, lower-risk polio vaccine may be on the horizon

March 11, 2025

University of Leeds researchers have taken a major step towards producing a more affordable and lower-risk polio vaccine using virus-like particles (VLPs). These particles mimic the outer protein shell of poliovirus, but are empty inside. […]

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