A collaborative research team led by Dr. Thorsten Schlaeger (Boston Children’s Hospital) Emiri Nakamura and Professor Koji Eto (Department of Clinical Application) has identified microtubule (MT) destabilization as a promising strategy to enhance platelet production from human iPS cell-derived immortalized megakaryocyte progenitor cell lines (imMKCLs). The work is published in PLOS One.
Destabilizing microtubules to boost platelet production from iPS cell-derived megakaryocytes
